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GF446-MG HumanKine® Thermostable bFGF,
Human Recombinant

Engineered bFGF growth factor with enchanced thermostability compared to the wild-type bFGF protein. Allows a less vigorous feeding schedule for human es/ips and neural stem cell culture.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P09038
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GF446-MG
1 mg  
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      Overview

      Replacement Information

      Key Spec Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF446-MG
      Trade Name
      • HumanKine®
      DescriptionHumanKine® Thermostable bFGF,
      Human Recombinant
      Alternate Names
      • FGF2
      • prostatropin
      • Prostatropin
      • HBGF-2
      • BFGF
      Background InformationThe HumanKine Thermostable bFGF is engineered with enchanced thermostability compared to the wild-type bFGF protein without modification of biological function.

      Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proliferation of human embryonic stem (hES) cells under feeder-free conditions.
      References
      Product Information
      PresentationLyophilized from a 0.2 μm filtered solution of 1X PBS.
      Quality LevelMQ100
      Applications
      ApplicationEngineered bFGF growth factor with enchanced thermostability compared to the wild-type bFGF protein. Allows a less vigorous feeding schedule for human es/ips and neural stem cell culture.
      Application NotesHumanKine products are Xeno-Free
      Biological Information
      PurityProduct is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line. EC50 is typically ≤0.5 ng/mL
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF446-MG 04053252976056

      Documentation

      HumanKine® Thermostable bFGF,
      Human Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      HumanKine® Thermostable bFGF,
      Human Recombinant Certificates of Analysis

      TitleLot Number
      HumanKine® Thermostable bFGF, -VP1410077 VP1410077
      HumanKine® Thermostable bFGF, -VP1605042 VP1605042
      HumanKine® Thermostable bFGF, -VP1606077 VP1606077
      HumanKine® Thermostable bFGF, Human Recombinant - VP2207137 VP2207137
      HumanKine® Thermostable bFGF, Human Recombinant - VP2412100 VP2412100
      HumanKine® Thermostable bFGF, Human Recombinant -VP1510288 VP1510288

      Technical Info

      Title
      HumanKine®Thermostable bFGF