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407715 Interleukin-13, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhIL-13

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407715
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Recombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. A potent regulator of STAT6 and JAK3 in NK and T cells. Regulates inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
      Catalogue Number407715
      Brand Family Calbiochem®
      SynonymsrhIL-13
      References
      ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
      Saura, M., et al. 1996. Biochem. J. 313, 641.
      Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
      Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
      McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
      Minty, A., et al. 1993. Nature 362, 248.
      Product Information
      CAS number148157-34-0
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, pH 7.4.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.5-2.5 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg IL-13
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      407715 0

      Documentation

      Interleukin-13, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Interleukin-13, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      407715

      References

      Reference overview
      Yu, C.R., et al. 1998. J. Immunol. 161, 218.
      Saura, M., et al. 1996. Biochem. J. 313, 641.
      Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
      Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
      McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
      Minty, A., et al. 1993. Nature 362, 248.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-December-2018 JSW
      SynonymsrhIL-13
      DescriptionRecombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. Potent regulator of inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, pH 7.4.
      CAS number148157-34-0
      Purity≥95% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/µg IL-13
      Biological activityED₅₀ = 0.5-2.5 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
      SolubilityReconstitute to a concentration of ≥5 µg/ml with sterile PBS.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
      Toxicity Standard Handling
      ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
      Saura, M., et al. 1996. Biochem. J. 313, 641.
      Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
      Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
      McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
      Minty, A., et al. 1993. Nature 362, 248.