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371956 Iso-H-7, Dihydrochloride

Iso-H-7, Dihydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl

371956
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.

      We are currently only offering the parent inhibitor, H-7, Dihydrochloride (Cat. No. 371955) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.





      Cell permable and less potent than H-7 in inhibiting rat brain protein kinase C isoforms (IC50 = 50 µM). Also inhibits cyclic-nucleotide-dependent protein kinases.
      Catalogue Number371956
      Brand Family Calbiochem®
      Synonyms1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl
      References
      ReferencesQuick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.
      Product Information
      CAS number140663-38-3
      FormFaint yellow lyophilized solid
      Hill FormulaC₁₄H₁₇N₃O₂S · 2HCl
      Chemical formulaC₁₄H₁₇N₃O₂S · 2HCl
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetPKC isoforms
      Primary Target IC<sub>50</sub>50 µM
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      371956 0

      Documentation

      References

      Reference overview
      Quick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision25-June-2008 JSW
      Synonyms1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl
      DescriptionCell-permeable and less potent than H-7 in inhibiting rat brain protein kinase C isoforms (IC50 = 50 µM). Also inhibits other cyclic-nucleotide-dependent protein kinases.
      FormFaint yellow lyophilized solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number140663-38-3
      Chemical formulaC₁₄H₁₇N₃O₂S · 2HCl
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
      Toxicity Standard Handling
      ReferencesQuick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.