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475842 L-Mimosine

L-Mimosine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: β-[N-(3-Hydroxy-4-pyridone)]-α-aminopropionic Acid, Leucenol

475842
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      500-44-7C₈H₁₀N₂O₄
      Description
      Overview

      This product has been discontinued.





      A naturally-occurring rare amino acid derivative isolated from Leucaena seeds. An extremely effective inhibitor of DNA replication in mammalian cells that may act by preventing the formation of replication forks. Inhibits the activity of mitochondrial and cytosolic serine hydroxymethyltransferases.
      Catalogue Number475842
      Brand Family Calbiochem®
      Synonymsβ-[N-(3-Hydroxy-4-pyridone)]-α-aminopropionic Acid, Leucenol
      References
      ReferencesLin, H.-B., et al. 1996. J. Biol. Chem. 271, 2548.
      Ebien, S.T., et al. 1995. Cancer Res. 55, 1994.
      Urbani, L., et al. 1995. Exp. Cell Res. 219, 159.
      Wang, Y., et al. 1995. Exp. Cell Res. 217, 84.
      Product Information
      CAS number500-44-7
      FormOff-white solid
      Hill FormulaC₈H₁₀N₂O₄
      Chemical formulaC₈H₁₀N₂O₄
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUT7610000
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      475842 0

      Documentation

      L-Mimosine Certificates of Analysis

      TitleLot Number
      475842

      References

      Reference overview
      Lin, H.-B., et al. 1996. J. Biol. Chem. 271, 2548.
      Ebien, S.T., et al. 1995. Cancer Res. 55, 1994.
      Urbani, L., et al. 1995. Exp. Cell Res. 219, 159.
      Wang, Y., et al. 1995. Exp. Cell Res. 217, 84.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-May-2008 RFH
      Synonymsβ-[N-(3-Hydroxy-4-pyridone)]-α-aminopropionic Acid, Leucenol
      DescriptionA naturally occurring rare amino acid derivative isolated from Leucaena seeds. An extremely effective inhibitor of DNA replication in mammalian cells that may act by preventing the formation of replication forks. Inhibits the activity of mitochondrial and cytosolic serine hydroxymethyltransferases (SHMT).
      FormOff-white solid
      CAS number500-44-7
      RTECSUT7610000
      Chemical formulaC₈H₁₀N₂O₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDilute acids or bases
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C).
      Toxicity Harmful
      Merck USA index14, 6199
      ReferencesLin, H.-B., et al. 1996. J. Biol. Chem. 271, 2548.
      Ebien, S.T., et al. 1995. Cancer Res. 55, 1994.
      Urbani, L., et al. 1995. Exp. Cell Res. 219, 159.
      Wang, Y., et al. 1995. Exp. Cell Res. 217, 84.