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444185 MAP Kinase Cascade Inhibitor Set

The MAP Kinase Cascade Inhibitor Set controls the biological activity of MAP Kinase Cascade. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MAP Kinase Cascade Inhibitor Set MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: MAP kinase
444185
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      Contains 1 mg each of FPT Inhibitor III (Cat. No. 344154) and ZM 336372 (Cat. No. 692000), 5 mg of PD 98059 (Cat. No. 513000) and 1 mg of SB 203580 (Cat. No. 559389).
      Catalogue Number444185
      Brand Family Calbiochem®
      References
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Primary TargetMAP kinase
      Primary Target IC<sub>50</sub>farnesyltransferase IC₅₀ = 2.6 µM
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      444185 0

      Documentation

      MAP Kinase Cascade Inhibitor Set Certificates of Analysis

      TitleLot Number
      444185

      Brochure

      Title
      Protein Kinase Assay and Detection Kits Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2008 RFH
      DescriptionThe mitogen-activated protein (MAP) kinases are a group of serine/threonine kinases that mediate signal transduction from the cell surface to the nucleus. They are activated in response to a variety of extracellular stimuli such as hormones, growth factors, UV, as well as osmotic and heat shock. Three main MAP kinase pathways have been characterized that are mediated by ERK, JNK and p38 MAP kinase, respectively. The four inhibitors included in this set allow you to target different stages of the ERK and p38 pathways.
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Toxicity Standard Handling