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MAGPMAG-24K MILLIPLEX MAP Mouse Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay

The analytes available for this multiplex kit are: sALK-1, Amphiregulin, Angiopoietin-2, Betacellulin, sCD31/PECAM-1, EGF, Endoglin, Endothelin-1, sFasL, FGF-2, Follistatin, G-CSF, HGF, IL-1β, IL-6, IL-17A, KC/CXCL1, Leptin, MCP-1, MIP-1α, & more

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Cancer
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MAGPMAG-24K
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Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsMultiplexing Ordering RequirementsDetection Methods
sALK-1 Amphiregulin Angiopoietin-2 Betacellulin sCD31/PECAM-1 EGF Endoglin Endothelin-1 sFasL FGF-2 Follistatin G-CSF HGF IL-1β IL-6 IL-17A KC/CXCL1 Leptin MCP-1 MIP-1α PLGF-2 Prolactin SDF-1 TNF-α VEGF-A VEGF-C VEGF-D MMplexPlease note: Sample Type must be selected when configuring this kit. Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples. Luminex xMAP
Description
Catalogue NumberMAGPMAG-24K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Mouse Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay
OverviewMILLIPLEX® MAP Mouse Angiogenesis//Growth Factor Magnetic Bead Panel, MAGPMAG-24K, is a 24-plex (for serum/plasma) or 27-plex (for cell culture) kit to be used for the simultaneous quantification of the following analytes: Angiopoietin-2, G-CSF, sFasL, sAlk-1, Amphiregulin, Leptin, IL-1b, Betacellulin, EGF, IL-6, Endoglin, Endothelin-1, FGF-2, Follistatin, HGF, PECAM-1, IL-17, PLGF-2, KC, MCP-1, Prolactin, MIP-1a, SDF-1, VEGF-C, VEGF-D, VEGF-A, and TNFα.
Background InformationAngiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra Assay: < 10
  • Inter Assay: < 15
Multiplex Ordering RequirementsPlease note: Sample Type must be selected when configuring this kit. Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples.
Panel TypeMAGNETIC Circulating Cancer
Quality LevelMQ200
Applications
ApplicationThe analytes available for this multiplex kit are: sALK-1, Amphiregulin, Angiopoietin-2, Betacellulin, sCD31/PECAM-1, EGF, Endoglin, Endothelin-1, sFasL, FGF-2, Follistatin, G-CSF, HGF, IL-1β, IL-6, IL-17A, KC/CXCL1, Leptin, MCP-1, MIP-1α, & more
Key Applications
  • Multiplexing
Application Notes• This is an overnight incubation assay requiring 25 µL of 1:2 dilution of plasma or serum, or 25 μL cell culture supernatant per well.
• This kit may be used for the analysis of all or any combination of the Mouse Angiogenesis/Growth Factor Panel analytes in serum, plasma or tissue/cell lysate and culture supernatant, with the following exception:
• Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples.
Biological Information
SpecificityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Species Reactivity
  • Mouse
Analytes Available
  • sALK-1
  • Amphiregulin
  • Angiopoietin-2
  • Betacellulin
  • sCD31/PECAM-1
  • EGF
  • Endoglin
  • Endothelin-1
  • sFasL
  • FGF-2
  • Follistatin
  • G-CSF
  • HGF
  • IL-1β
  • IL-6
  • IL-17A
  • KC/CXCL1
  • Leptin
  • MCP-1
  • MIP-1α
  • PLGF-2
  • Prolactin
  • SDF-1
  • TNF-α
  • VEGF-A
  • VEGF-C
  • VEGF-D
Assay PanelEverything you need in a single kit.
Accuracy
  • 90% - 104%
Physicochemical Information
Sensitivity
  • Refer to kit protocol for sensitivities of individual analytes.
Standard Curve Range
  • sALK-1 14 – 10,000 pg/mL
  • Amphiregulin 7 – 5,000 pg/mL
  • Angiopoietin-2 27 – 20,000 pg/mL
  • Betacellulin 7 – 5,000 pg/mL
  • sCD31/ PECAM-1 14 – 10,000 pg/mL
  • EGF 27 – 20,000 pg/mL
  • Endoglin 27 – 20,000 pg/mL
  • Endothelin-1 1 – 1,000 pg/mL
  • sFasL 69 – 50,000 pg/mL
  • FGF-2/FGF-basic 69 – 50,000 pg/mL
  • Follistatin 137 – 100,000 pg/mL
  • G-CSF 7 – 5,000 pg/mL
  • HGF 137 – 100,000 pg/mL
  • IL-1b 14 – 10,000 pg/mL
  • IL-6 7 – 5,000 pg/mL
  • IL-17A 7 – 5,000 pg/mL
  • KC/CXCL1 7 – 5,000 pg/mL
  • Leptin 14 – 10,000 pg/mL
  • MCP-1 27 – 20,000 pg/mL
  • MIP-1α 14 – 10,000 pg/mL
  • PLGF-2 3 – 2,000 pg/mL
  • Prolactin 69 – 50,000 pg/mL
  • SDF-1 137 – 100,000 pg/mL
  • TNFα 6 – 4,000 pg/mL
  • VEGF-A 6 – 4,000 pg/mL
  • VEGF-C 27 – 20,000 pg/mL
  • VEGF-D 69 – 50,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAGPMAG-24K 04053252987724

Documentation

Protocols

Title
Protocol- MAGPMAG-24K

MILLIPLEX MAP Mouse Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

Brochure

Title
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Range Sheet- MAGP-108 and MAGP-208
Quality Control Range Sheet- MAGP-109 and MAGP-209
Quality Control Ranges: Mouse Angiogenesis Growth Factor Magnetic Bead Panel

Posters

Title
Utility of human and mouse multiplex immunoassay panels for studying profiles of circulating angiogenic factors as biomarkers for angiogenesis research