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474925 MY-5445

MY-5445 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-(3-Chlorophenylamino)-4-phenylphthalazine

Primary Target: CGMP-PDEV
474925
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      78351-75-4C₂₀H₁₄ClN₃
      Description
      Overview

      This product has been discontinued.





      A cell-permeable, selective inhibitor of cGMP-specific phosphodiesterase (PDE V; IC50 = 600 nM).
      Catalogue Number474925
      Brand Family Calbiochem®
      Synonyms1-(3-Chlorophenylamino)-4-phenylphthalazine
      References
      ReferencesAkamatsu, N., et al. 1993. J. Neuroendocrinol. 5, 517.
      Durate, I.D., et al. 1990. Eur. J. Pharmacol. 186, 289.
      Hagiwara, M., et al. 1989. J. Pharmacol. Exp. Ther. 228, 467.
      Product Information
      CAS number78351-75-4
      FormGreenish-yellow solid
      Hill FormulaC₂₀H₁₄ClN₃
      Chemical formulaC₂₀H₁₄ClN₃
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetCGMP-PDEV
      Primary Target IC<sub>50</sub>600 nM
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      474925 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      MY-5445 SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Akamatsu, N., et al. 1993. J. Neuroendocrinol. 5, 517.
      Durate, I.D., et al. 1990. Eur. J. Pharmacol. 186, 289.
      Hagiwara, M., et al. 1989. J. Pharmacol. Exp. Ther. 228, 467.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-August-2008 RFH
      Synonyms1-(3-Chlorophenylamino)-4-phenylphthalazine
      DescriptionA cell-permeable, selective inhibitor of cGMP-specific phosphodiesterase (PDE V, IC50 = 600 nM).
      FormGreenish-yellow solid
      CAS number78351-75-4
      Chemical formulaC₂₀H₁₄ClN₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (5 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Irritant
      ReferencesAkamatsu, N., et al. 1993. J. Neuroendocrinol. 5, 517.
      Durate, I.D., et al. 1990. Eur. J. Pharmacol. 186, 289.
      Hagiwara, M., et al. 1989. J. Pharmacol. Exp. Ther. 228, 467.