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495417 N-Oleoyl Ethanolamine - CAS 111-58-0 - Calbiochem

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA

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495417
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
111-58-0C₂₀H₃₉NO₂

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495417-25MG
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      Description
      OverviewA potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
      Catalogue Number495417
      Brand Family Calbiochem®
      SynonymsN-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
      References
      ReferencesPahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
      Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
      Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.
      Product Information
      CAS number111-58-0
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₀H₃₉NO₂
      Chemical formulaC₂₀H₃₉NO₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAcid ceramidase
      Primary Target IC<sub>50</sub>~ 500 µM against acid ceramidase
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      495417-25MG 04055977199727

      Documentation

      N-Oleoyl Ethanolamine - CAS 111-58-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      N-Oleoyl Ethanolamine - CAS 111-58-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      495417

      References

      Reference overview
      Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
      Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
      Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-August-2008 RFH
      SynonymsN-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
      DescriptionA potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
      FormWhite solid
      CAS number111-58-0
      Chemical formulaC₂₀H₃₉NO₂
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityEthanol (5 mg/ml), Chloroform (5 mg/ml), or Methanol (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesPahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
      Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
      Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.