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482675 Nitric Oxide Donor Set

Contains 20 mg of (±)-S-Nitroso-N-acetylpenicillamine, 10 mg of NOR-3, 10 mg of 4-Phenyl-3-furoxancarbonitrile, 20 mg of SIN-1, Hydrochloride, and 100 mg of Sodium Nitroprusside.

Nitric Oxide Donor Set MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
482675
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      Contains 20 mg of (±)-S-Nitroso-N-acetylpenicillamine (SNAP; Cat. No. 487910), 10 mg of NOR-3 (Cat. No. 489530), 10 mg of 4-Phenyl-3-furoxancarbonitrile, 20 mg of SIN-1, Hydrochloride (Cat. No. 567028), and 100 mg of Sodium Nitroprusside (Cat. No. 567538). Supplied with a data sheet.
      Catalogue Number482675
      Brand Family Calbiochem®
      References
      ReferencesWink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
      Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
      Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
      Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
      Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
      Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
      Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
      Hino, N., et al. 1989. J. Antibiot. 42, 1578.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 26/27/28-36/37/38

      Very toxic by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 22-36/37/39-45-26

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Multiple Toxicity Values, refer to MSDS
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsSIN-1, NOR-3, SNAP, and 4-Phenyl-3-furoxancarbonitrile are not stable in solution and should be reconstituted just prior to use. Stock solutions of sodium nitroprusside for up to 2 weeks at 4°C in the dark. NOR-3, 4-Phenyl-3-furoxancarbonitrile, sodium nitroprusside, and SNAP should be protected from light.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      482675 0

      Documentation

      Nitric Oxide Donor Set Certificates of Analysis

      TitleLot Number
      482675

      References

      Reference overview
      Wink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
      Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
      Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
      Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
      Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
      Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
      Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
      Hino, N., et al. 1989. J. Antibiot. 42, 1578.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-August-2008JSW
      DescriptionNitric oxide (NO) is an intracellular messenger molecule with multiple regulatory functions, including neurotransmission, control of blood pressure, platelet aggregation, smooth muscle relaxation, and macrophage-mediated cytotoxicity. Calbiochem® offers a wide variety of NO donors for the study of these intracellular pathways. Now we have packaged several of our most popular NO donors into one convenient set. The table below lists the biological properties of these compounds. Supplied with a data sheet.
      FormSolid
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsSIN-1, NOR-3, SNAP, and 4-Phenyl-3-furoxancarbonitrile are not stable in solution and should be reconstituted just prior to use. Stock solutions of sodium nitroprusside for up to 2 weeks at 4°C in the dark. NOR-3, 4-Phenyl-3-furoxancarbonitrile, sodium nitroprusside, and SNAP should be protected from light.
      Toxicity Multiple Toxicity Values, refer to MSDS
      ReferencesWink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
      Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
      Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
      Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
      Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
      Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
      Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
      Hino, N., et al. 1989. J. Antibiot. 42, 1578.