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573094 P3-AHNP Peptide Carrier

573094
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      The cell-permeant peptide carrier that has been used successfully to target ErbB2-overexpressing cancer cells. The carrier construct is composed of a 9-aa TAT-derived internalization sequence (P3), a glycine spacer, and a 12-aa anti-HER-2/neu peptide mimetic (AHNP). An essential control for P3-AHNP-based deliveries, such as studies that utilize P3-AHNP-STAT3BP (Cat. No. 573092).
      Catalogue Number573094
      Brand Family Calbiochem®
      SynonymsH-YGRKKRRQR-G-FCDGFYACYKDV-OH, Cyclic, P3-anti-HER-2/neu peptide mimetic
      References
      ReferencesTan, M., et al. 2006. Cancer Res. 66, 3764.
      Product Information
      DeclarationSold under license of U.S. Patent 7,179,785.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₄₀H₂₀₈N₄₁O₃₈PS₂
      Chemical formulaC₁₄₀H₂₀₈N₄₁O₃₈PS₂
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide SequenceH₂N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Gly-Phe-Cys-Asp-Gly-Phe-Tyr-Ala-Cys-Tyr-Lys-Asp-Val-CO₂H, Cyclic
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      573094 0

      Documentation

      P3-AHNP Peptide Carrier Certificates of Analysis

      TitleLot Number
      573094

      References

      Reference overview
      Tan, M., et al. 2006. Cancer Res. 66, 3764.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-March-2009 RFH
      SynonymsH-YGRKKRRQR-G-FCDGFYACYKDV-OH, Cyclic, P3-anti-HER-2/neu peptide mimetic
      DescriptionThe cell-permeant peptide carrier that has been used successfully to target ErbB2-overexpressing cancer cells. The carrier construct is composed of a 9-aa TAT-derived internalization sequence (P3), a glycine spacer, and a 12-aa anti-HER-2/neu peptide mimetic (AHNP). An essential control for P3-AHNP-based deliveries, such as studies that utilize P3-AHNP-STAT3BP (Cat. No. 573092).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₄₀H₂₀₈N₄₁O₃₈PS₂
      Peptide SequenceH₂N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Gly-Phe-Cys-Asp-Gly-Phe-Tyr-Ala-Cys-Tyr-Lys-Asp-Val-CO₂H, Cyclic
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTan, M., et al. 2006. Cancer Res. 66, 3764.