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203678 PKG Substrate, BPDEtide

PKG Substrate, BPDEtide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Protein Kinase G Substrate, RKISASEFDRPLR

203678
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      Sequence derived from bovine lung cGMP-specific phosphodiesterase (cG-BPDE). A specific and sensitive substrate for PKG (Km = 68 µM) relative to PKA (Km = 320 µM). Not phosphorylated by PKC or by CaM kinase II.
      Catalogue Number203678
      Brand Family Calbiochem®
      SynonymsProtein Kinase G Substrate, RKISASEFDRPLR
      References
      ReferencesGertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
      Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
      Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
      Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₆₈H₁₁₅N₂₃O₂₀
      Chemical formulaC₆₈H₁₁₅N₂₃O₂₀
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Arg-Lys-Ile-Ser-Ala-Ser-Glu-Phe-Asp-Arg-Pro-Leu-Arg-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      203678 0

      Documentation

      PKG Substrate, BPDEtide Certificates of Analysis

      TitleLot Number
      203678

      References

      Reference overview
      Gertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
      Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
      Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
      Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-January-2008 JSW
      SynonymsProtein Kinase G Substrate, RKISASEFDRPLR
      DescriptionSequence derived from bovine lung cGMP-specific phosphodiesterase (cG-BPDE). A specific substrate for PKG (Km = 68 µM) relative to PKA (Km = 320 µM). Not phosphorylated by PKC or by CaM kinase II.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₆₈H₁₁₅N₂₃O₂₀
      Peptide SequenceH-Arg-Lys-Ile-Ser-Ala-Ser-Glu-Phe-Asp-Arg-Pro-Leu-Arg-OH
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
      Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
      Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
      Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.