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506125 Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem

Paroxetine Hydrochloride is a very potent uptake inhibitor highly selective for 5-HT transporter.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-HT transporter, Paroxetine, Paxil

Primary Target: 5-HT Uptake Transporter
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506125
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
110429-35-1C₁₉H₂₀FNO₃·HCl

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      		 Glass bottle 10 mg
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      Description
      OverviewA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
      Catalogue Number506125
      Brand Family Calbiochem®
      Synonyms5-HT transporter, Paroxetine, Paxil
      References
      ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
      Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
      Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
      Product Information
      CAS number110429-35-1
      FormWhite solid
      Hill FormulaC₁₉H₂₀FNO₃·HCl
      Chemical formulaC₁₉H₂₀FNO₃·HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target5-HT Uptake Transporter
      Primary Target K<sub>i</sub>0.065 nM
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.06125.0001 04055977243109

      Documentation

      Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
      Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
      Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-December-2018 JSW
      Synonyms5-HT transporter, Paroxetine, Paxil
      DescriptionA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
      FormWhite solid
      CAS number110429-35-1
      Chemical formulaC₁₉H₂₀FNO₃·HCl
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
      Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
      Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.