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504840 (R)-CPPene - CAS 117414-74-1 - Calbiochem

(R)-CPPene - CAS 117414-74-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel

Primary Target: NMDA receptors
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      117414-74-1C₈H₁₅N₂O₅P
      Description
      Overview

      This product has been discontinued.



      A highly potent competitive antagonist of NMDA receptors (ED50 = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain.
      Catalogue Number504840
      Brand Family Calbiochem®
      Synonyms(R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel
      References
      ReferencesLowe, D., et al. 1990. Neurosci. Lett. 113, 315.
      Bullock, R., et al. 1990. Stroke. 21, 32.
      Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
      Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
      Duty, S. 2012. CNS Drugs 26, 1017.
      Product Information
      CAS number117414-74-1
      FormWhite solid
      Hill FormulaC₈H₁₅N₂O₅P
      Chemical formulaC₈H₁₅N₂O₅P
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNMDA receptors
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      504840 0

      Documentation

      (R)-CPPene - CAS 117414-74-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Lowe, D., et al. 1990. Neurosci. Lett. 113, 315.
      Bullock, R., et al. 1990. Stroke. 21, 32.
      Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
      Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
      Duty, S. 2012. CNS Drugs 26, 1017.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSW
      Synonyms(R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel
      DescriptionA highly potent competitive antagonist of NMDA receptors (ED50 = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain.
      FormWhite solid
      CAS number117414-74-1
      Chemical formulaC₈H₁₅N₂O₅P
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLowe, D., et al. 1990. Neurosci. Lett. 113, 315.
      Bullock, R., et al. 1990. Stroke. 21, 32.
      Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
      Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
      Duty, S. 2012. CNS Drugs 26, 1017.