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565625 SC-68376 - CAS 318480-82-9 - Calbiochem

SC-68376 - CAS 318480-82-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Methyl-4-phenyl-5-(4-pyridyl)oxazole

Primary Target: p38MAPK
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      318480-82-9C₁₅H₁₂N₂O
      Description
      Overview

      This product has been discontinued.



      A potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase activity in a dose-dependent manner (IC50 = 2-5 µM). Does not inhibit basal ERK or IL-1-induced JNK activity.
      Catalogue Number565625
      Brand Family Calbiochem®
      Synonyms2-Methyl-4-phenyl-5-(4-pyridyl)oxazole
      References
      ReferencesGuan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
      Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.
      Product Information
      CAS number318480-82-9
      ATP CompetitiveY
      FormWhite to yellow semi-solid
      Hill FormulaC₁₅H₁₂N₂O
      Chemical formulaC₁₅H₁₂N₂O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetp38MAPK
      Primary Target IC<sub>50</sub>2-5 µM against p38MAP kinase activity
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      565625 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      SC-68376 - CAS 318480-82-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      SC-68376 - CAS 318480-82-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      565625

      References

      Reference overview
      Guan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
      Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-January-2010 RFH
      Synonyms2-Methyl-4-phenyl-5-(4-pyridyl)oxazole
      DescriptionPotently, reversible, cell-permeable, ATP-competitive and selectively inhibits p38 mitogen-activated protein kinase (MAPK) activity in a dose-dependent manner (IC50 = 2-5 µM). Does not inhibit basal ERK or IL-1-induced JNK activity.
      FormWhite to yellow semi-solid
      CAS number318480-82-9
      Chemical formulaC₁₅H₁₂N₂O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (200 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesGuan, Z., et al. 1998. J. Biol. Chem. 273, 12901.
      Guan, Z., et al. 1997. J. Biol. Chem. 272, 8083.