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572300 Stromal Cell-Derived Factor 1α, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhSDF-1α, PBSF, Pre-B Cell Growth Stimulating Factor

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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Recombinant, human SDF-1α (amino acids 22-89) expressed in E. coli. Chemoattractant for T lymphocytes and monocytes. A member of the CXC family that binds to the CXCR4 receptor and has been shown to be a potent inhibitor of infection by lymphocyte-tropic HIV-1 strains. Attracts mature lymphocytes to the bone marrow and may be involved in graft rejection.
      Catalogue Number572300
      Brand Family Calbiochem®
      SynonymsrhSDF-1α, PBSF, Pre-B Cell Growth Stimulating Factor
      References
      ReferencesElisseeva, E.L., et al. 2000. J. Biol. Chem. 275, 26799.
      Bleul, C., et al. 1996. Nature 382, 829.
      Oberlin, E., et al. 1996. Nature 382, 833.
      Tashiro, K., et al. 1993. Science 261, 600.
      Product Information
      FormLyophilized
      FormulationLyophilized from a sterile-filtered solution of 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhSDF-1α.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 3-9 ng/ml as measured by its ability to chemoattract 5-10 day cultured human T lymphocytes
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1 EU/µg cytokine
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      572300 0

      Documentation

      Stromal Cell-Derived Factor 1α, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Stromal Cell-Derived Factor 1α, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      572300

      References

      Reference overview
      Elisseeva, E.L., et al. 2000. J. Biol. Chem. 275, 26799.
      Bleul, C., et al. 1996. Nature 382, 829.
      Oberlin, E., et al. 1996. Nature 382, 833.
      Tashiro, K., et al. 1993. Science 261, 600.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-July-2008 RFH
      SynonymsrhSDF-1α, PBSF, Pre-B Cell Growth Stimulating Factor
      DescriptionRecombinant, human SDF-1α (amino acids 22-89) expressed in E. coli. Chemoattractant for T-lymphocytes and monocytes. Binds to the CXCR4 receptor and has been shown to be a potent inhibitor of infection by lymphocyte-tropic HIV-1 strains.
      FormLyophilized
      FormulationLyophilized from a sterile-filtered solution of 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhSDF-1α.
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: ≤1 EU/µg cytokine
      Biological activityED₅₀ = 3-9 ng/ml as measured by its ability to chemoattract 5-10 day cultured human T lymphocytes
      SolubilityReconstitute to a concentration ≥10 µg/ml with sterile PBS, ≥0.1% HSA or BSA.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
      Toxicity Standard Handling
      ReferencesElisseeva, E.L., et al. 2000. J. Biol. Chem. 275, 26799.
      Bleul, C., et al. 1996. Nature 382, 829.
      Oberlin, E., et al. 1996. Nature 382, 833.
      Tashiro, K., et al. 1993. Science 261, 600.