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612084 TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem

Native TIMP-2 from human rheumatoid synovial fibroblast.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Tissue Inhibitor of Metalloproteinase-2

Primary Target: MMP-1
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      Overview

      Replacement Information
      Description
      OverviewNative TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
      Catalogue Number612084
      Brand Family Calbiochem®
      SynonymsTissue Inhibitor of Metalloproteinase-2
      References
      ReferencesGreene, J., et al. 1996. J. Biol. Chem. 271, 30375.
      Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-1
      Purity≥90% by SDS-PAGE
      SourcePrepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      612084 0

      Documentation

      TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      TIMP-2, Human Rheumatoid Synovial Fibroblast - Calbiochem Certificates of Analysis

      TitleLot Number
      612084

      References

      Reference overview
      Greene, J., et al. 1996. J. Biol. Chem. 271, 30375.
      Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsTissue Inhibitor of Metalloproteinase-2
      DescriptionNative TIMP-2 from human rheumatoid synovial fibroblast. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Shown to inhibit the activities of MMP-1, MMP-2, MMP-12, and transin.
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, pH 7.0.
      SourcePrepared from fibroblasts that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥90% by SDS-PAGE
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Toxicity Standard Handling
      ReferencesGreene, J., et al. 1996. J. Biol. Chem. 271, 30375.
      Miyazaki, K., et al. 1993. J. Biol. Chem. 268, 14387.