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851088 TOTU

TOTU Novabiochem®. CAS 136849-72-4, molar mass 328.07 g/mol.

TOTU MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 136849-72-4 Molar Mass: 328.07 g/mol Hill Formula: C₁₀H₁₇BF₄N₄O₃
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851088
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
136849-72-4C₁₀H₁₇BF₄N₄O₃328.07 g/mol
Description
Catalogue Number851088
Brand Family Novabiochem®
Alternate Names
  • O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,NÆ,NÆ-tetramethyluronium tetrafluoroborate
Background InformationTOTU is an excellent alternative to HOBt-based coupling reagents such as HBTU and TBTU. It has high reactivity and is likely to have low allergenicity and low explosivity. The by-products of using this coupling reagent are water-soluble, making it an ideal choice for solution phase coupling reactions.
References
Product Information
CAS number136849-72-4
Hill FormulaC₁₀H₁₇BF₄N₄O₃
Molar Mass328.07 g/mol
HS Code2926 90 99
Quality LevelMQ200
Applications
ApplicationTOTU Novabiochem®. CAS 136849-72-4, molar mass 328.07 g/mol.
Biological Information
Physicochemical Information
Melting Point142 - 148 °C
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 500 - 650 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H302: Harmful if swallowed.
H317: May cause an allergic skin reaction.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.
Precautionary Statement(s)P261: Avoid breathing dust.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/ eye protection/ face protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P501: Dispose of contents/ container to an approved waste disposal plant.
Signal WordDanger
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Categories of dangerharmful
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)conforms
Assay (HPLC, area%)≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clear soluble

Documentation

TOTU SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] G. Breipohl & W. Koenig, US patent 5166394.