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855074 Weinreb AM resin

Novabiochem®

Weinreb AM resin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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855074
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Overview

Replacement Information
Description
Catalogue Number855074
Replaces01-64-0153
Brand Family Novabiochem®
Alternate Names
  • N-Fmoc- N-methoxy-β-alanine AM resin
Background InformationThis support is useful for the production of peptide aldehydes and other carboxaldehydes. Following removal of the Fmoc group with 20% piperidine in DMF, acylation of the resin-bound methoxylamine is best effected using DIPCDI/HOAt or HATU/DIPEA activation. This results in formation of a supported Weinreb-type amide which can be either reduced to an aldehyde with LiAlH4 [1, 2] or cleaved with Grignard reagents to give ketones [2, 3].

The product number for this product was previously 01-64-0153.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore below +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF)0.40 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂)lot specific result
The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh

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Categories

Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Resins for Solid Phase Peptide Synthesis > Resins for Fmoc SPPS of Carboxy-modified Peptides > Peptide Aldehydes
Reagents, Chemicals and Labware > Novabiochem® Peptide and DNA Synthesis Reagents > Resins for Solid Phase Organic Chemistry > NH2, NH2NH Functionalized Resins > Resins Cleaved by Hydrides and Organometallic Reagents