Certificate of Analysis 1.05802 HX85399502
- Document Type:
- Certificate of Analysis
- Lot Number:
- HX85399502
- Product Catalog Number:
- 1.05802
1.05802
10 Results
Advanced Search
Showing
Narrow Your Results Use the filters below to refine your search
Document Type
-
-
Certificate of Analysis 1.05802 HX71984702
- Document Type:
- Certificate of Analysis
- Lot Number:
- HX71984702
- Product Catalog Number:
- 1.05802
-
COA 105802
- Document Type:
- Certificate of Analysis
- Product Catalog Number:
- 105802
-
Higher intramuscular triacylglycerol in women does not impair insulin sensitivity and proximal insulin signaling.
- Women have been shown to have higher muscle triacylglycerol (IMTG) levels than men and could therefore be expected to have lower insulin sensitivity than men, since previous studies have linked high IMTG to decreased insulin sensitivity. Therefore, insulin sensitivity of whole body and leg glucose uptake was studied in 9 women in the follicular phase and 8 men on a controlled diet and matched for maximal oxygen uptake per kilogram of lean body mass and habitual activity level. A 47% higher (P 0.05) IMTG level was found in women than in men, and, at the same time, women also displayed 22% higher whole body insulin sensitivity (P 0.05) and 29% higher insulin-stimulated leg glucose uptake (P = 0.05) during an euglycemic-hyperinsulinemic ( approximately 70 muU/ml) clamp compared with matched male subjects. The higher insulin sensitivity in women could not be explained by higher expression of muscle glucose transporter GLUT4, insulin receptor, or Akt expression or by the ability of insulin to stimulate Akt Thr(308) or Akt Ser(473) phosphorylation. However, a 30% higher (P 0.05) capillary density and 31% more type 1 muscle fiber expressed per area in the vastus lateralis muscle were noted in women than in matched men. It is concluded that despite 47% higher IMTG levels in women in the follicular phase, whole body as well as leg insulin sensitivity are higher than in matched men. This was not explained by sex differences in proximal insulin signaling in women. In women, it seems that a high capillary density and type 1 muscle fiber expression may be important for insulin action.
- Document Type:
- Reference
- Product Catalog Number:
- 05-802
-
Luxplate - a bright idea for brilliant results!
- Document Type:
- Brochure
- Product Catalog Number:
- Multiple
-
Fast and Precise. Thin Layer Chromatography by.
- Document Type:
- Brochure
- Product Catalog Number:
- Multiple
- Product Catalog Name:
- Multiple