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851029 N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms)

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
1205744-09-7C₂₅H₄₄N₄O₈S * C₈H₁₉N698.95 g/mol
Description
Catalogue Number851029
Replaces01-63-0133
Brand Family Novabiochem®
Alternate Names
  • O-(N-Biotinyl-3-aminopropyl)-O'-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA
Background InformationThe use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.

The product number for this product was previously 01-63-0133.

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References
Product Information
CAS number1205744-09-7
Hill FormulaC₂₅H₄₄N₄O₈S * C₈H₁₉N
Molar Mass698.95 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Melting Point131 - 136 °C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Purity (TLC(CMA2))≥ 98 %
Assay (HPLC, area%)≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP)clearly soluble
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