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852092 Fmoc-Dab(Mtt)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
851392-68-2C₃₉H₃₆N₂O₄596.71 g/mol
Description
Catalogue Number852092
Replaces04-12-1210
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-γ-4-methyltrityl-L-diaminobutanoic acid
Background InformationThe side-chain Mtt group can be selectively removed with 1% TFA in DCM [1, 2, 3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis of branched peptides and peptides modified at the Dab side-chain [4, 5], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.

The product number for this product was previously 04-12-1210.

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References
Product Information
CAS number851392-68-2
Hill FormulaC₃₉H₃₆N₂O₄
Molar Mass596.71 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Dab(Mtt)-OH Novabiochem®. CAS 851392-68-2, molar mass 596.71 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.0 % (a/a)
Purity (TLC(011A))≥ 95 %
Assay (HPLC, area%)≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Water (K. F.)≤ 1.0 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Dab(Mtt)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283.
  • [2] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488.
  • [3] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264.
  • [4] K. Barlos, personal communication.
  • [5] P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436.
  • [6] C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257.