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Reactive nitrogen species contribute to blood-labyrinth barrier disruption in suppurative labyrinthitis complicating experimental pneumococcal meningitis in the rat
Document Type:

Reference

Product Catalog Number:

06-284
Product Catalog Name:

Anti-Nitrotyrosine Antibody
High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation.
In plants, root nitrate uptake systems are under systemic feedback repression by the N satiety of the whole organism, thus adjusting the N acquisition capacity to the N demand for growth; however, the underlying molecular mechanisms are largely unknown. We previously isolated the Arabidopsis high nitrogen-insensitive 9-1 (hni9-1) mutant, impaired in the systemic feedback repression of the root nitrate transporter NRT2.1 by high N supply. Here, we show that HNI9 encodes Arabidopsis INTERACT WITH SPT6 (AtIWS1), an evolutionary conserved component of the RNA polymerase II complex. HNI9/AtIWS1 acts in roots to repress NRT2.1 transcription in response to high N supply. At a genomic level, HNI9/AtIWS1 is shown to play a broader role in N signaling by regulating several hundred N-responsive genes in roots. Repression of NRT2.1 transcription by high N supply is associated with an HNI9/AtIWS1-dependent increase in histone H3 lysine 27 trimethylation at the NRT2.1 locus. Our findings highlight the hypothesis that posttranslational chromatin modifications control nutrient acquisition in plants.
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Reference

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Multiple
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Multiple
Nitrogen (total) according to Kjeldahl
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Application

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Nitrogen (total) in dairy products
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Multiple
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Multiple
Nitrogen (total) in effluents
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Multiple
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Multiple
Nitrogen (total) according to Kjeldahl (Water & sludge)
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Multiple
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Multiple
Nitrogen (total) in soils
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Multiple
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Nitrogen (total) in fish meal
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Nitrogen (total) according to Kjeldahl (Others)
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Application

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Multiple
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Multiple
Reactive oxygen nitrogen species decrease cystic fibrosis transmembrane conductance regulator expression and cAMP-mediated Cl- secretion in airway epithelia♪A mutation in ...
Document Type:

Reference

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple