histone+h2a
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Histone Modifications | Life Science Research | Merck
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. The most commonly studied histone modifications are acetylation, phosphorylation, methylation, and ubiquitination. -
Histones and Histone Modifications | Life Science Research | Merck
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today. -
Genomic instability | Life Science Research | Merck
Learn about the environmental factors that can hinder DNA repair. There are many evidence linking genomic and epigenomic changes to disorders involving accelerated aging. Evidence points to general physiological stress and disrupted circadian. It is also possible that decreased DNA repair is also a symptom, not a cause, of aging. To investigate this possibility, researchers will need to examine changes in transcriptional regulators of repair genes, such as ncRNAs, hormones, and other chromatin modulators. -
Flow Cytometry Kits for Cell Signaling | Life Science Research | Merck
Our Milli-Mark Antibodies provide an accurate examination of Cell Signaling Pathways to understand the cause of various diseases. FlowCellect Kits evaluate Cell Cycle changes. -
Bulk Antibodies | Life Science Research | Merck
Choose from thousands of bulk reagents Antibodies for a range of research areas. These reagents are ideal for long term manufacturing and research projects. -
DNA Structure, Damage and Repair | Life Science Research | Merck
Studying the mechanisms by which cells control changes in DNA structure and respond to DNA damage will help to elucidate the factors that cause aging, cellular degeneration, cancer, and death. Merck has the antibody solutions you need for your research. -
Flow Cytometry Applications - Cell Health | Life Science | Merck
Monitoring the impact on mitochondria and related cell health markers applications is an important part of drug screening programs, pathway mapping, apoptosis, and disease research. -
Cell Signaling Assays for Muse Cell Analyzer | Life Science Research | Merck
Muse signaling assays were developed to give researchers a rapid, simple method for detecting the activation of key signaling pathways in cell populations.