nitrat Search Results - International

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114556 - Certificate of Quality - Spectroquant Nitrate Cell Test in seawater / Nitrat-Küvettentest in Seewasser / Test en cubetas Nitratos en agua de mar
Document Type:

Certificate

Product Catalog Number:

114556
Product Catalog Name:

Nitrate Cell Test in seawater
114773 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos
Document Type:

Certificate

Product Catalog Number:

114773
Product Catalog Name:

Nitrate Test
101842 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos
Document Type:

Certificate

Product Catalog Number:

101842
Product Catalog Name:

Nitrate Test
109713 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos
Document Type:

Certificate

Product Catalog Number:

109713
Product Catalog Name:

Nitrate Test
Label 117961 RQeasy Nitrate Test / Nitrat-Test
Document Type:

User Guide
Nitrate in Waste Water
Document Type:

Application

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple
A Nitrate Ester of Sedative Alkyl Alcohol Improves Muscle Function and Structure in a Murine Model of Duchenne Muscular Dystrophy.
Nitric oxide (NO) has major physiological and cellular effects on muscle growth, repair, and function. In most muscle biopsies from humans with myopathies, sarcolemma-localized neuronal nitric oxide synthase (nNOS) is either reduced or not detected, particularly in dystrophin-deficient Duchenne muscular dystrophy (DMD). Abnormal NO signaling at the sarcolemmal level is integrally involved in the pathogenesis and accounts, at least in part, for the muscle weakness of DMD. Dystrophic muscle fibers exhibit an increased susceptibility to contraction-induced membrane damage. Muscle relaxants function to prevent muscle wasting by decreasing nerve impulses and reducing calcium influx that regulates tensing or tightening of muscle fibers. We have recently developed a new class of nitric esters that combines the pharmacological functions of NO and muscle relaxation. Here, we report the synthesis and properties of the nitric ester (MMPN) of 2-methyl-2-n-propyl-1,3-propanediol (MPP) and its effect in mdx dystrophic mice, a murine model of DMD. MMPN produced significant improvements in biochemical, pathological, and functional phenotypes in the mouse model. The endurance of exercise was extended by 47% in time to exhaustion and 84% in running distance. Serum CK level was decreased by 30%. Additionally, MMPN decreased intracellular free calcium concentration without causing skeletal muscle weakness. No hepatic or renal toxicities were observed during the study. Our investigations unveil a potential new treatment for muscular diseases.
Document Type:

Reference

Product Catalog Number:

AB3239
Nitrate in Beetroot Juice
Document Type:

Application

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple
Nitrate Spectroquant Test Kits Equivalency Checklist for Laboratories 2017
Document Type:

Technical Information
Nitrate in Carrot Juice (Beverages)
Document Type:

Application

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple

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114556 - Certificate of Quality - Spectroquant Nitrate Cell Test in seawater / Nitrat-Küvettentest in Seewasser / Test en cubetas Nitratos en agua de mar

114773 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos

101842 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos

109713 - Certificate of Quality - Spectroquant Nitrate Test / Nitrat-Test / Test Nitratos

Label 117961 RQeasy Nitrate Test / Nitrat-Test

Nitrate in Waste Water

A Nitrate Ester of Sedative Alkyl Alcohol Improves Muscle Function and Structure in a Murine Model of Duchenne Muscular Dystrophy.

Nitrate in Beetroot Juice

Nitrate Spectroquant Test Kits Equivalency Checklist for Laboratories 2017

Nitrate in Carrot Juice (Beverages)

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