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Merck

182028

Poly(ethylene glycol)

greener alternative

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

別名:

PEO

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この商品について

化学式:
(-CH2CH2O-)n
CAS番号:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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製品名

ポリ(エチレンオキシド), average Mv 600,000 (nominal), powder

form

powder

Quality Level

mol wt

average Mv 600,000 (nominal)

contains

200-500 ppm BHT as inhibitor

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

viscosity

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

transition temp

Tm 65 °C

Ω-end

hydroxyl

α-end

hydroxyl

application(s)

battery manufacturing

greener alternative category

SMILES string

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

ポリ(エチレンオキシド)(PEO)は、高分子量の非イオン性水溶性ポリマーです。水和するとゲルを形成し、優れた膨潤能力を示します。PEOポリマーは毒性がなく、薬物の溶解性を高めるため、薬物送達システムで広く使用されています。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

ポリ(エチレンオキシド)は、以下の製造に使用できます。
  • 持続的な薬物放出のための生体吸収性および注射可能なヒドロゲル。
  • 燃料電池用のPEO/酸化グラフェン複合電解質膜。
  • ポリ(エチレンオキシド)-b-ポリ(ε-カプロラクトン)(PEO-b-PCL)ジブロックコポリマー。ロサルタンカリウムカプセル化(PEO-b-PCL)コポリマーは、薬物担体として使用できます。


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保管分類

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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資料

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

すべての記事を見る

Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced