A4926
1,2-ビス(2-アミノフェノキシ)エタン-N,N,N′,N′-四酢酸
98%
別名:
2,2′-(エチレンジオキシ)ジアニリン-N,N,N′,N′-四酢酸, BAPTA, エチレンジオキシビス(o-フェニレンニトリロ)四酢酸
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この商品について
実験式（ヒル表記法）:
C22H24N2O10
CAS番号:
分子量:
476.43
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5192406
Quality Segment
assay
98%
form
powder
density
±1.494 g/cm3 at 25 °C (Predicted)
storage temp.
2-8°C
SMILES string
OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O
InChI
1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
InChI key
FTEDXVNDVHYDQW-UHFFFAOYSA-N
General description
自然界では、1,2-ビス(2-アミノフェノキシ)エタン-N,N,N′,N′-テトラ酢酸（BAPTA）は、ラットにおける脳虚血の神経保護剤であるBAPTA-AM（BAPTA-テトラアセトキシメチルエステル）の主な代謝産物です。BAPTAは細胞間Ca2+キレート剤です。
Application
The product can be used in various R&D applications such as:
Neuroscience: Used to suppress intracellular Ca2+ overload, reduce neuronal apoptosis, and preserve electrophysiological function in injury models, demonstrating strong neuroprotective action.
Pharmacology: Enables precise buffering of intracellular Ca2+ levels, allowing researchers to distinguish Ca2+‑ dependent drug effects and dissect therapeutic signaling mechanisms.
Neuroscience: Used to suppress intracellular Ca2+ overload, reduce neuronal apoptosis, and preserve electrophysiological function in injury models, demonstrating strong neuroprotective action.
Pharmacology: Enables precise buffering of intracellular Ca2+ levels, allowing researchers to distinguish Ca2+‑ dependent drug effects and dissect therapeutic signaling mechanisms.
Other Notes
pKa: 1.401 ± 0.10 (predicted)
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保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves