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この商品について
実験式（ヒル表記法）:
C36H69NO8
CAS番号:
分子量:
643.93
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
製品名
C12 Glucosyl(β) Ceramide (d18:1/12:0), Avanti Research™ - A Croda Brand 860543P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860543P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860543P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
InChI
1S/C36H69NO8/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-30(39)29(28-44-36-35(43)34(42)33(41)31(27-38)45-36)37-32(40)26-24-22-20-17-12-10-8-6-4-2/h23,25,29-31,33-36,38-39,41-43H,3-22,24,26-28H2,1-2H3,(H,37,40)/b25-23+/t29-,30+,31?,33+,34?,35?,36+/m0/s1
InChI key
IYCYEZLMOLRFAN-QGJHTTTBSA-N
Application
C12 Glucosyl(β) Ceramide (d18:1/12:0) or D-glucosyl-β-1,1′-N-lauroyl-D-erythro-sphingosine has been used in lipid binding assay to assess the binding of monoclonal antibodies (mAbs). It may be used as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis. It may also be used as an internal standard for lipid extraction in U87MG (human glioma cell line).
Packaging
5 mL Amber Glass Screw Cap Vial (860543P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類
11 - Combustible Solids
wgk
WGK 3
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Hernandez-Tiedra S, et al.
Autophagy, 12(11), 2213-2229 (2016)
Shelly J Krebs et al.
Immunity, 50(3), 677-691 (2019-03-17)
Lineage-based vaccine design is an attractive approach for eliciting broadly neutralizing antibodies (bNAbs) against HIV-1. However, most bNAb lineages studied to date have features indicative of unusual recombination and/or development. From an individual in the prospective RV217 cohort, we identified
David B Iaea et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158609-158609 (2020-01-10)
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well