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Merck

48-625MAG

MILLIPLEX® Phospo/Total mTOR Signaling Panel

Premixed mTOR Phospo/Total 2-Plex Cell Signaling Panel

Synonym(s):

PI3K/mTOR pathway, mTOR ELISA, mTOR assay, mTOR kinase assay, mTOR multiplex panel, mTOR phosphorylation, mTOR signaling, mammalian target of rapamycin, total mTOR

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Product Name

MILLIPLEX® Phospo/Total mTOR Signaling Panel,

Quality Segment

description

Premixed mTOR Phospo/Total 2-Plex Cell Signaling Panel

species reactivity

human, rat, mouse

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

mTOR is a serine/threonine kinase that integrates signals from nutrients, growth factors, and energy status to regulate cell growth and metabolism. Phosphorylation at Ser2448 reflects mTOR activation and its role in protein synthesis and autophagy.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 2 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: mTOR (Phospho-Ser2448), mTOR (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Features and Benefits

  • Quantifies both phospho and total mTOR in a single reaction
  • Enables analysis of mTOR pathway activity in cancer and metabolic research
  • High sensitivity for low-abundance targets
  • Efficient use of precious samples with multiplexing capability

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


signalword

Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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