MILLIPLEX^® MAPK/SAPK Signaling Panel

This panel focuses on phosphorylated proteins within the MAPK and SAPK pathways, which regulate cellular responses to stress, growth factors, and cytokines. ERK1/2 (pT185/pY187), JNK (pT183/pY185), and p38 (pT180/pY182) are core MAPKs involved in proliferation, apoptosis, and inflammation. MEK1 (pS217/pS221) activates ERK, while MSK1 (pS376) and RSK1 (pS380) are downstream effectors. c-Jun (pS73) and ATF2 (pT71) are transcription factors regulated by JNK and p38. HSP27 (pS82) and MKK3/6 (pS189/pS207) are involved in stress response and MAPK activation.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 10 analytes in cell lysate samples.

Analytes Included: ERK1/2 (pT185/pY187), JNK (pT183/pY185), p38 (pT180/pY182), MEK1 (pS217/pS221), MSK1 (pS376), RSK1 (pS380), c-Jun (pS73), ATF2 (pT71), HSP27 (pS82), MKK3/6 (pS189/pS207)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate^™).

Luminex is a registered trademark of Luminex Corp

MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.