主要文書

すべての文書を表示

5.08436

AEBSF Hydrochloride

Name: AEBSF Hydrochloride
Brand: MM

≥97% (HPLC), serine proteases inhibitor, liquid

別名:

InSolution AEBSF, Hydrochloride, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl, AEBSF, HCl InSolution

ログインで組織・契約価格をご覧ください。

サイズを選択してください

表示を変更する

この商品について

実験式（ヒル表記法）:

C₈H₁₀FNO₂S · xHCl

CAS番号:

30827-99-7

分子量:

203.23 (free base basis)

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00132962

Assay:

≥97% (HPLC)

Form:

liquid

Storage condition:

OK to freeze, avoid repeated freeze/thaw cycles, protect from light

テクニカルサービス

お困りのことがあれば、経験豊富なテクニカルサービスチームがお客様をサポートします。

お手伝いします

特性

製品名

AEBSF Hydrochloride, InSolution, ≥97%, Specific, irreversible inhibitor of serine proteases

Quality Segment

100

assay

≥97% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles, protect from light

storage temp.

−70°C

SMILES string

F[S](=O)(=O)c1ccc(cc1)CCN.[Cl-].[H+]

InChI

1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H

InChI key

WRDABNWSWOHGMS-UHFFFAOYSA-N

詳細

General description

Specific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPU_α) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications.

Biochem/physiol Actions

Reversible: no

Packaging

Packaged under inert gas

Physical form

A 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride (Cat. No. 101500) in H₂O.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 1 year at -20°C.

Other Notes

Citron, M., et al. 1996. Neuron17, 171.
Ohkubo, I., et al. 1994. J. Biochem.116, 1182.
Mintz, G.R. 1993. BioPharm.6, 34.
Lawson, W.B., et al. 1982. Folia Haematol.109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol.23, 2247.
Markwardt, F., et al. 1973. Thromb. Res.2, 343.

Baker, B.R., and Cory, M. 1971. J. Med. Chem.14, 119.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Still not finding the right product?

Explore all of our products under AEBSF Hydrochloride

pictograms

GHS07

signalword

Warning

hcodes

H315,H319

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

保管分類

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c