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Merck

535140

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

別名:

Animal free Protease inhibitor

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この商品について

UNSPSC Code:
12352200
NACRES:
NA.54
Form:
liquid
Solubility:
water: soluble
Storage temp.:
−20°C

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製品名

Protease Inhibitor Cocktail Set III, Animal-Free, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

solubility

water: soluble

shipped in

wet ice

storage temp.

−20°C

関連するカテゴリー

General description

A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 80 µM Aprotinin (Cat. No. 616371), 5 mM Bestatin (Cat. No. 200484), 1.5 mM E-64 (Cat. No. 324890), 2 mM Leupeptin Hemisulfate (Cat. No. 108975) and 1 mM Pepstatin A (Cat. No. 516482). Available as 1 ml vial or a set of 5 x 1 ml.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Aspartic, cysteine, and serine proteases as well as aminopeptidases
Product does not compete with ATP.
Reversible: no

Physical form

In 1 ml DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

保管分類

10 - Combustible liquids

wgk

WGK 2

flash_point_f

188.6 °F

flash_point_c

87 °C

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

535140-1SET: + 535140-1SML: + 535140-1ML:

jan

試験成績書（COA）

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Li-Ping Gao et al.
ACS chemical neuroscience, 11(5), 814-829 (2020-02-13)
Mitophagy is an important process for removing damaged mitochondria in cells, the dysfunction of which has been directly linked to an increasing number of neurodegenerative disorders. However, the details of mitophagy in prion diseases still need to be deeply explored.
Ching-Hsin Huang et al.
Advanced therapeutics, 3(6) (2021-03-02)
Mono- or dual-checkpoint inhibitors for immunotherapy have changed the paradigm of cancer care; however, only a minority of patients responds to such treatment. Combining small molecule immuno-stimulators can improve treatment efficacy, but they are restricted by poor pharmacokinetics. In this
Aarthi Gunasekaran et al.
Pediatric research, 87(7), 1177-1184 (2019-09-10)
Disruption of tight junctions (TJs) predisposes to bacterial translocation, intestinal inflammation, and necrotizing enterocolitis (NEC). Previously, studies showed that hyaluronan (HA), a glycosaminoglycan in human milk, maintains intestinal permeability, enhances intestinal immunity, and reduces intestinal infections. In this study, we
Eunju Shin et al.
Biochemical and biophysical research communications, 528(1), 46-53 (2020-05-28)
GATA1 is a master transcription factor of megakaryopoiesis and erythropoiesis, and loss-of-function mutation can induce accumulation of megakaryocyte-erythroid progenitors (MEPs) in mice and humans. Accordingly, the murine MEP cell line (termed G1ME2 cells) encoding doxycycline (dox)-inducible anti-Gata1 shRNA on Hprt
Dong-Min Kim et al.
Cell reports, 37(1), 109798-109798 (2021-09-30)
Despite the worldwide effect of the coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we show that critical COVID-19 is associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases. In addition, we
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グローバルトレードアイテム番号

カタログ番号GTIN
535140-1SETCN07790788051235
535140-1MLCN04055977076141

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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