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Merck

AB5087

Anti-Melanocyte Stimulating Hormone α Antibody

serum, Chemicon®

別名:

alpha-MSH, POMC, Pro-opiomelanocortin, Corticotropin-lipotropin precursor

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, RIA
Citations:
66
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biological source

sheep

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, radioimmunoassay: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... POMC(5443)

Immunogen

MSH conjugated with bovine thyroglobulin.

Application

Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.
Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue.

RIA: 1:250,000-1:300,000.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Biochem/physiol Actions

Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal.

Physical form

Sheep Serum. Liquid. Contains no preservative.
Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Hypothalamus

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

AB5087:

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
Amanda H Mortensen et al.
Human molecular genetics, 24(4), 939-953 (2014-10-16)
OTX2 is a homeodomain transcription factor that is necessary for normal head development in mouse and man. Heterozygosity for loss-of-function alleles causes an incompletely penetrant, haploinsufficiency disorder. Affected individuals exhibit a spectrum of features that range from developmental defects in
B E Grayson et al.
Endocrinology, 151(4), 1622-1632 (2010-02-24)
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system. To study the effects of chronic maternal
Gavin A Bewick et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(12), 1680-1682 (2005-08-16)
Agouti-related protein (AgRP) and neuropeptide Y (NPY) are colocalized in arcuate nucleus (arcuate) neurons implicated in the regulation of energy balance. Both AgRP and NPY stimulate food intake when administered into the third ventricle and are up-regulated in states of

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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