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Merck

AB5087

Anti-Melanocyte Stimulating Hormone α Antibody

serum, Chemicon®

別名:

alpha-MSH, POMC, Pro-opiomelanocortin, Corticotropin-lipotropin precursor

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
radioimmunoassay
Technique(s):
immunohistochemistry: suitable
radioimmunoassay: suitable
Citations:
66
Uniprot accession no.:
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製品名

Anti-Melanocyte Stimulating Hormone α Antibody, serum, Chemicon®

biological source

sheep

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
radioimmunoassay: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... POMC(5443)

Analysis Note

Control
Hypothalamus

Application

Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.
Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue.

RIA: 1:250,000-1:300,000.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Biochem/physiol Actions

Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

MSH conjugated with bovine thyroglobulin.

Physical form

Sheep Serum. Liquid. Contains no preservative.
Unpurified

Preparation Note

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

AB5087:

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Processing and sorting of the prohormone convertase 2 propeptide.
Muller, L; Cameron, A; Fortenberry, Y; Apletalina, EV; Lindberg, I
The Journal of Biological Chemistry null
Shona L Kirk et al.
PloS one, 4(6), e5870-e5870 (2009-06-12)
Hypothalamic systems which regulate appetite may be permanently modified during early development. We have previously reported hyperphagia and increased adiposity in the adult offspring of rodents fed an obesogenic diet prior to and throughout pregnancy and lactation. We now report
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Gavin A Bewick et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(12), 1680-1682 (2005-08-16)
Agouti-related protein (AgRP) and neuropeptide Y (NPY) are colocalized in arcuate nucleus (arcuate) neurons implicated in the regulation of energy balance. Both AgRP and NPY stimulate food intake when administered into the third ventricle and are up-regulated in states of

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