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この商品について
化学式:
CH3C(=NOH)COCH3
CAS番号:
分子量:
101.10
UNSPSC Code:
41116105
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-348-5
Beilstein/REAXYS Number:
605582
MDL number:
InChI key
FSEUPUDHEBLWJY-HWKANZROSA-N
InChI
1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+
SMILES string
CC(=O)\C(C)=N\O
assay
≥98.0% (N), ≥99.0%
form
solid
quality
for spectrophotometric det. of urea
technique(s)
UV/Vis spectroscopy: suitable
ign. residue
≤0.05% (as SO4)
bp
185-186 °C (lit.)
mp
75-76 °C, 75-78 °C (lit.)
Quality Level
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関連するカテゴリー
General description
2,3-Butanedione Monoxime (BDM) is also known as diacetyl monoxime, it is also a nucleophilic agent and it can dephosphorylates acetylcholinesterase poisoned with organophosphates. It is also a well-characterized, non-competitive inhibitor of skeletal muscle myosin-II, where it inhibits the chemical and motile activity.
Application
- A novel method to extend viability and functionality of living heart slices.: This research introduces a novel application of 2,3-Butanedione monoxime for prolonging the functional lifespan of cardiac tissue samples in experimental settings, offering insights into cardiac biology and potential therapeutic targets (Ross et al., 2023).
- Molecular Mechanisms of Deregulation of Muscle Contractility Caused by the R168H Mutation in TPM3 and Its Attenuation by Therapeutic Agents.: The study utilizes 2,3-Butanedione monoxime to investigate the molecular pathways affected by genetic mutations in muscle contractility, contributing to the understanding of muscle disorders and their management (Karpicheva et al., 2023).
- Generation of myocyte agonal Ca(2+) waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation.: Research employing 2,3-Butanedione monoxime investigates its role in inducing specific cellular events in cardiac cells under stress, highlighting its potential in studies of heart disease mechanisms and therapies (Morishita et al., 2023).
Analysis Note
溶解度:
10 mLの水または10 mLのエタノールに0.5 gが完全に溶解し、透明溶液となります。
感度分析:
0.05 mgの尿素を3 mLの水、5 mL濃塩酸、3%ジアセチルモノキシム水溶液とともに水浴で10分間加熱すると、淡黄色の溶液が得られます。
10 mLの水または10 mLのエタノールに0.5 gが完全に溶解し、透明溶液となります。
感度分析:
0.05 mgの尿素を3 mLの水、5 mL濃塩酸、3%ジアセチルモノキシム水溶液とともに水浴で10分間加熱すると、淡黄色の溶液が得られます。
Other Notes
Reagent for the colorimetric determination of urea and ureido-compounds; Spectrometric reagent for Co(II), Ni(II), Pd(II) and Re(VII); Reagent for the gravimetric determination of Ni(II)
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
31550-25G: + 31550-100G: + 31550-500G: + 31550-VAR: + 31550-BULK:
jan
W.B. Guenther
Analytical Letters, 12A, 1305-1305 (1979)
2, 3-Butanedione monoxime (BDM) as a myosin inhibitor.
Ostap EM.
Journal of Muscle Research and Cell Motility, 23 (4), 305-308 (2002)
Improvements on the Prescott-Jones method for the colorimetric analysis of ureido compounds.
D B Shindler et al.
Analytical biochemistry, 97(2), 421-422 (1979-09-01)
Chang Liu et al.
Molecular plant, 11(11), 1389-1399 (2018-10-09)
The process of pollen germination is crucial for flowering plant reproduction, but the mechanisms through which pollen grains establish polarity and select germination sites are not well understood. In this study, we report that a formin family protein, AtFH5, is localized
Multiple Effects of 2, 3-Butanedione Monoxime.
Sellin LC and McArdle JJ/
Pharmacology & Toxicology, 74 (4-5), 305-313 (1994)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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