89458
Aphidicolin
analytical standard
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この商品について
実験式（ヒル表記法）:
C20H34O4
CAS番号:
分子量:
338.48
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
Quality Level
grade
analytical standard
assay
≥95% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
storage temp.
2-8°C
SMILES string
C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@]23CC[C@]4(O)CO
InChI
1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
InChI key
NOFOAYPPHIUXJR-APNQCZIXSA-N
General description
Aphidicolin is a diterpenoid metabolite of the fungi, Cephalosporium aphidicola and Phoma betae. It is known to be an antiviral drug and inhibits the incorporation of thymidine into DNA of cultured human embryonic lung cells.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Aphidicolin may be used as a reference standard in the determination of the analyte in plasma samples using gas chromatography coupled with mass spectrometry (GC-MS).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chemistry of Fungi (2008)
Aphidicolin: A specific inhibitor of DNA polymerases in the cytosol of rat liver.
Ohashi M, et al.
Biochemical and Biophysical Research Communications, 82(4), 1084-1090 (1978)
A gas chromatographic mass spectrometric assay for the determination of aphidicolin in plasma of cancer patients.
Journal of Pharmaceutical Sciences, 78(5), 399-401 (1989)