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Merck

B018

WB-4101 hydrochloride

analytical standard

別名:

2-[(2,6-Dimethoxyphenoxyethyl)aminomethyl]-1,4-benzodioxane hydrochloride

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この商品について

実験式(ヒル表記法):
C19H23NO5 · HCl
CAS番号:
分子量:
381.85
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
218-520-3
MDL number:
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InChI key

KAHMEWANVDFFCQ-UHFFFAOYSA-N

InChI

1S/C19H23NO5.ClH/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14;/h3-9,14,20H,10-13H2,1-2H3;1H

SMILES string

Cl.COc1cccc(OC)c1OCCNCC2COc3ccccc3O2

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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試験成績書(COA)

Lot/Batch Number

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

K Ichishima et al.
British journal of pharmacology, 161(1), 193-206 (2010-08-20)
Volume-regulated anion channels (VRACs) play an important role in cell-volume regulation. alpha(1)-Adrenoceptor stimulation by phenylephrine (PE) suppressed the hypotonic activation of VRAC current in mouse ventricular cells and regulatory volume decrease (RVD) was also absent in PE-treated cells. We examined
Jin O-Uchi et al.
Circulation research, 102(11), 1378-1388 (2008-05-10)
We examined the effect of alpha(1)-adrenoceptor subtype-specific stimulation on L-type Ca2+ current (I(Ca)) and elucidated the subtype-specific intracellular mechanisms for the regulation of L-type Ca2+ channels in isolated rat ventricular myocytes. We confirmed the protein expression of alpha(1A)- and alpha(1B)-adrenoceptor
W-X Yuan et al.
Neuroscience, 158(4), 1616-1624 (2008-12-11)
Activation of the descending noradrenergic system inhibits nociceptive transmission in the spinal cord. Although both alpha(1)- and alpha(2)-adrenoceptors in the spinal cord are involved in the modulation of nociceptive transmission, it is not clear how alpha(1)-adrenoceptors regulate excitatory and inhibitory
F H F Alves et al.
Neuroscience, 177, 74-83 (2011-01-12)
Dynamic exercise evokes sustained blood pressure and heart rate (HR) increases. Although it is well accepted that there is a CNS mediation of cardiovascular adjustments during dynamic exercise, information on the role of specific CNS structures is still limited. The
Josie R T Silva et al.
The journal of pain : official journal of the American Pain Society, 12(1), 51-60 (2010-06-18)
We evaluated the effectiveness of intrathecal antagonists of α1- (WB4101) and α2- (idazoxan) adrenoceptors and serotonergic (methysergide), opioid (naloxone), muscarinic (atropine), GABA(A) (bicuculline) and GABA(B) (phaclofen) receptors in blocking 2- or 100-Hz electroacupuncture (EA)-induced analgesia (EAIA) in the rat tail-flick

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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