T5428
テトラメチルローダミンメチルエステルパークロレート
≥95% purity, powder
別名:
TMRM
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この商品について
化学式:
C25H25N2O3 · ClO4
CAS番号:
分子量:
500.93
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
7162165
製品名
テトラメチルローダミンメチルエステルパークロレート, ≥95%
Quality Segment
assay
≥95%
form
powder
composition
Carbon: 57.5-62.4%
Nitrogen: 5.3-5.9%
technique(s)
titration: suitable
color
dark green
solubility
methanol: 5 mg/mL, clear
εmax
>95000 at 546-552 nm in methanol
fluorescence
λem 573 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
SMILES string
[O-]Cl(=O)(=O)=O.COC(=O)c1ccccc1C2=C3C=C\C(C=C3Oc4cc(ccc24)N(C)C)=[N+](\C)C
InChI
1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChI key
PFYWPQMAWCYNGW-UHFFFAOYSA-M
General description
テトラメチルローダミンメチルエステル過塩素酸塩（TMRM）は、ミトコンドリアを標識し、胚性幹細胞／誘導多能性幹細胞由来の心筋細胞をマークできる膜透過性のカチオン性蛍光色素です。成熟した心筋細胞の単離に役立ちます。
Application
テトラメチルローダミンメチルエステル過塩素酸塩（TMRM）は、ミトコンドリア膜電位を検出するための高感度プローブとして使用されています。
保管分類
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
資料
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity
Kaytee L
PLoS ONE (2016)
Markus Hartl et al.
Molecular systems biology, 13(10), 949-949 (2017-10-25)
Histone deacetylases have central functions in regulating stress defenses and development in plants. However, the knowledge about the deacetylase functions is largely limited to histones, although these enzymes were found in diverse subcellular compartments. In this study, we determined the
Yuejiao Ma et al.
Journal of cell science, 132(15) (2019-07-11)
Mitochondrial remodelling is a central feature of stem cell differentiation. However, little is known about the regulatory mechanisms during these processes. Previously, we found that a pharmacological inhibitor of glycogen synthase kinase-3α and -3β, CHIR-99021, initiates human adipose stem cell