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Merck

90878

ポリエチレングリコール

greener alternative

BioUltra, 300

別名:

PEG

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この商品について

化学式:
H(OCH2CH2)nOH
CAS番号:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

viscous liquid

mol wt

Mr 285-315

Quality Level

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

refractive index

n20/D 1.465

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.125 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06, λ: 280 nm Amax: 0.03

greener alternative category

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application


  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: This study explores the use of Poly(ethylene glycol) (PEG) in creating a lyophilized eukaryotic cell-free protein expression system. The research demonstrates how PEG facilitates the stabilization and preservation of cell-free systems, enhancing protein synthesis capabilities for various biochemical applications (Alfaro-Palma et al., 2024).

  • High-Contrast Luminescent Immunohistochemistry Using PEGylated Lanthanide Complexes.: The application of PEGylated lanthanide complexes in immunohistochemistry significantly improves the contrast and specificity of luminescent signals. This innovation aids in more accurate biochemical analysis and diagnostics (Su et al., 2022).

  • Analyzing Immune Response to Engineered Hydrogels by Hierarchical Clustering of Inflammatory Cell Subsets.: This research investigates the immune responses to PEG-based hydrogels used in tissue engineering. It provides insights into the biocompatibility and inflammatory reactions, essential for designing advanced biomaterials (Fernandez-Yague et al., 2022).

  • Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood.: The study shows how PEGylation of nanoparticles affects their interaction with immune cells, influencing drug delivery systems and therapeutic efficacy in biochemistry and molecular biology (Ju et al., 2020).

  • A Post-Insertion Strategy for Surface Functionalization of Bacterial and Mammalian Cell-Derived Extracellular Vesicles.: This paper discusses the post-insertion method using PEG for surface functionalization of extracellular vesicles, enhancing their potential for targeted drug delivery and biochemical research (Jiang et al., 2021).

保管分類

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

第4類:引火性液体 + 第四石油類 + 危険等級III

fsl

90878-250ML-F: + 90878-1L-F: + 90878-BULK-F: + 90878-VAR-F:

jan


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Vural Tagal et al.
Nature communications, 8, 14098-14098 (2017-01-20)
Mutations in the SMARCA4/BRG1 gene resulting in complete loss of its protein (BRG1) occur frequently in non-small cell lung cancer (NSCLC) cells. Currently, no single therapeutic agent has been identified as synthetically lethal with SMARCA4/BRG1 loss. We identify AURKA activity
Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.
Tine Cuppens et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 23(5), 1274-1285 (2017-02-25)
Hongge Wang et al.
Oncogene, 39(14), 2905-2920 (2020-02-08)
PARP1 and PARP2 play critical roles in regulating DNA repair and PARP inhibitors have been approved for the treatment of BRCA1/2-mutated ovarian and breast cancers. It has long been known that PARP inhibition sensitizes cancer cells to DNA-damaging cytotoxic agents
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro

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