A4477
Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
別名:
Anti-phospho-AMPA Glutamate Receptor 1 (pSer845)
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この商品について
Conjugate:
unconjugated
Clone:
polyclonal
Application:
DB, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen 100 kDa
species reactivity
human, rat
technique(s)
dot blot: 1:1000, western blot: 1:1,000 using rat brain extracts
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer845)
Quality Level
Gene Information
human ... GRIA1(2890)
rat ... Gria1(50592)
General description
AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.
Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody recognizes human and rat AMPA Receptor, GluR1 subunit (pSer845).
Immunogen
synthetic phosphorylated peptide corresponding to a region near serine 845 of rat glutamate receptor subunit GluR1.
Application
Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody can be used for western blot analysis at 1:1,000 using rat brain extracts.
Physical form
Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 μg/ml BSA and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
A4477-VAR: + A4477-100UL: + A4477-150UL: + A4477-BULK: + A4477-150UL-PW:
jan
Rodrigo Bainy Leal et al.
Molecular psychiatry, 25(3), 655-665 (2018-06-09)
Fear is a conscious state caused by exposure to real or imagined threats that trigger stress responses that affect the body and brain, particularly limbic structures. A sub-group of patients with mesial temporal lobe epilepsy related to hippocampus sclerosis (MTLE-HS)
Kuang-Ti Chen et al.
Frontiers in behavioral neuroscience, 9, 162-162 (2015-07-08)
Sarcosine, an endogenous amino acid, is a competitive inhibitor of the type I glycine transporter and an N-methyl-d-aspartate receptor (NMDAR) coagonist. Recently, we found that sarcosine, an NMDAR enhancer, can improve depression-related behaviors in rodents and humans. This result differs
Loukia Parisiadou et al.
Nature neuroscience, 17(3), 367-376 (2014-01-28)
Leucine-rich repeat kinase 2 (LRRK2) is enriched in the striatal projection neurons (SPNs). We found that LRRK2 negatively regulates protein kinase A (PKA) activity in the SPNs during synaptogenesis and in response to dopamine receptor Drd1 activation. LRRK2 interacted with
M W Lopes et al.
Translational psychiatry, 6(12), e986-e986 (2016-12-14)
Glucocorticoids (GC) released during stress response exert feedforward effects in the whole brain, but particularly in the limbic circuits that modulates cognition, emotion and behavior. GC are the most commonly prescribed anti-inflammatory and immunosuppressant medication worldwide and pharmacological GC treatment
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