A6855
Arachidonoyl-AMC
fatty acid amide hydrolase substrate, 99% (HPLC), solid
別名:
AAMCA
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この商品について
実験式（ヒル表記法）:
C30H39NO3
分子量:
461.64
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
製品名
Arachidonoyl-AMC, fatty acid amide hydrolase substrate
SMILES string
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
InChI key
IQPBUDMTXHWSHB-ZKWNWVNESA-N
InChI
1S/C30H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-29(32)31-26-21-22-27-25(2)23-30(33)34-28(27)24-26/h7-8,10-11,13-14,16-17,21-24H,3-6,9,12,15,18-20H2,1-2H3,(H,31,32)/b8-7-,11-10-,14-13-,17-16-
assay
99% (HPLC)
form
solid
storage condition
under inert gas
solubility
DMSO: soluble
storage temp.
−20°C
Quality Level
Application
Fluorogenic substrate used in a selective and sensitive assay of fatty acid amide hydrolase (FAAH).
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Simona Di Martino et al.
Journal of medicinal chemistry, 63(7), 3634-3664 (2020-03-17)
Sphingolipids (SphLs) are a diverse class of molecules that are regulated by a complex network of enzymatic pathways. A disturbance in these pathways leads to lipid accumulation and initiation of several SphL-related disorders. Acid ceramidase is one of the key
Enrico Dainese et al.
Scientific reports, 10(1), 2292-2292 (2020-02-12)
Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FAAH monomers likely allows both subunits to simultaneously recruit
Xinwen Zhang et al.
Neuropharmacology, 128, 269-281 (2017-10-25)
Monoacylglycerol lipase (MGL) hydrolyzes 2-arachidonoylglycerol to arachidonic acid and glycerol. Inhibition of MGL may attenuate neuroinflammation by enhancing endocannabinoid signaling and decreasing prostaglandin (PG) production. Almost half of HIV infected individuals are afflicted with HIV-associated neurocognitive disorder (HAND), a neuroinflammatory
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