biological source
rabbit skin
Quality Level
description
acid soluble
form
powder
technique(s)
cell culture | stem cell: suitable
solubility
aqueous acid: ≤10 mg/mL, aqueous sodium acetate buffer: soluble (0.01-0.5M)
UniProt accession no.
storage temp.
2-8°C
Gene Information
rabbit ... COL1A2(100008997)
General description
コラ-ゲンは構造や遺伝子が異なる多数のタイプに分類されています。シグマでは、BornsteinとTraubが提唱した命名法を使用しています。シグマのタイプ分けは一般的なコラ-ゲン分類とは異なりますのでご注意ください。
Application
I型コラーゲンは、広範な生体材料工学研究において、in vitroで幹細胞を増殖させる骨格として利用されてきました。
Preparation Note
Gallop, P.M.の方法の変法に従って調製されています。
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Prasad L Polavarapu et al.
Chirality, 23(9), 801-807 (2011-12-03)
Fourier transform infrared vibrational circular dichroism (FTIR-VCD) measurements have gone through major advances in the last decade. A major thrust in these advances was to find ways that can minimize the VCD spectral artifacts and obtain the VCD signals at
Katarina Wolf et al.
The Journal of cell biology, 201(7), 1069-1084 (2013-06-27)
Cell migration through 3D tissue depends on a physicochemical balance between cell deformability and physical tissue constraints. Migration rates are further governed by the capacity to degrade ECM by proteolytic enzymes, particularly matrix metalloproteinases (MMPs), and integrin- and actomyosin-mediated mechanocoupling.
Emily Hams et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 367-372 (2013-12-18)
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for interleukin (IL)-25 in the generation of