N4779
5-ニトロ-2-(3-フェニルプロピルアミノ)安息香酸
≥98%, chloride channel blocker, solid
別名:
NPPB
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この商品について
実験式（ヒル表記法）:
C16H16N2O4
CAS番号:
分子量:
300.31
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
製品名
5-ニトロ-2-(3-フェニルプロピルアミノ)安息香酸, ≥98%
Quality Level
assay
≥98%
form
solid
solubility
ethanol: 3 mg/mL, DMSO: 37 mg/mL, H2O: insoluble
storage temp.
−20°C
SMILES string
OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O
InChI
1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
InChI key
WBSMIPAMAXNXFS-UHFFFAOYSA-N
Biochem/physiol Actions
強力な塩素イオンチャネルブロッカ-です。
Features and Benefits
この化合物は、Handbook of Receptor Classification and Signal Transduction（受容体分類およびシグナル伝達ハンドブック）のChloride Channels（塩素チャネル）のページに記載されています。ハンドブックのその他のページをご覧になるには、こちらをクリックしてください。
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保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Michael R Bristow et al.
JACC. Basic to translational science, 5(9), 871-883 (2020-08-25)
Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that mRNA expression of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) cardiac myocyte receptor ACE2 is up-regulated with remodeling and with reverse
Agnieszka Dyrda et al.
PloS one, 5(2), e9447-e9447 (2010-03-03)
The mechanical, rheological and shape properties of red blood cells are determined by their cortical cytoskeleton, evolutionarily optimized to provide the dynamic deformability required for flow through capillaries much narrower than the cell's diameter. The shear stress induced by such
Anaïs Merckx et al.
PLoS pathogens, 4(2), e19-e19 (2008-02-06)
Malaria symptoms occur during Plasmodium falciparum development into red blood cells. During this process, the parasites make substantial modifications to the host cell in order to facilitate nutrient uptake and aid in parasite metabolism. One significant alteration that is required