P1851
PIPES
BioPerformance Certified, suitable for cell culture
別名:
1,4-ピペラジンジエタンスルホン酸, ピペラジン-1,4-ビス(2-エタンスルホン酸), ピペラジン-N,N′-ビス(2-エタンスルホン酸)
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この商品について
実験式（ヒル表記法）:
C8H18N2O6S2
CAS番号:
分子量:
302.37
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
227-057-6
Beilstein/REAXYS Number:
817713
MDL number:
Quality Level
grade
BioPerformance Certified, Molecular Biology
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin and Total Aerobic Microbial Count, tested
useful pH range
6.1-7.5
pKa (25 °C)
6.8
mp
>300 °C (lit.)
solubility
1 M NaOH: 20 + 80 mL g, clear, colorless, soluble
application(s)
diagnostic assay manufacturing
foreign activity
DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
SMILES string
OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
InChI
1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
InChI key
IHPYMWDTONKSCO-UHFFFAOYSA-N
Application
- リアルタイム等温示差走査蛍光定量法による免疫グロブリン G 安定性の高感度検出：抗体ベースの治療におけるタンパク質安定性の決定因子：示差走査蛍光測定における免疫グロブリン G の安定性維持には、PIPES バッファーの使用が不可欠です。この方法は、抗体ベースの治療薬の安定性を評価するために極めて重要です（Moggridge et al., 2017）。
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保管分類
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Veronique Adoue et al.
Molecular systems biology, 10, 754-754 (2014-10-19)
Most complex disease-associated genetic variants are located in non-coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis-regulatory impact (cis-rSNPs). We used
Leticia A Montoya et al.
Analytical chemistry, 86(12), 6032-6039 (2014-05-24)
Sulfhydryl-containing compounds, including thiols and hydrogen sulfide (H2S), play important but differential roles in biological structure and function. One major challenge in separating the biological roles of thiols and H2S is developing tools to effectively separate the reactivity of these
V D Prokopieva et al.
Alcohol and alcoholism (Oxford, Oxfordshire), 35(1), 44-48 (2000-02-24)
The effects of carnosine and related compounds on erythrocytes from alcoholics were studied. In their presence, erythrocytes showed an increased ability to resist haemolysis and showed a more normal morphology, with carnosine and N-acetyl-carnosine being the most effective compounds. These