R4528
抗hnRNP-A1抗体, マウスモノクローナル
clone 9H10, purified from hybridoma cell culture
別名:
抗不均一核リボ核タンパク質A1抗体
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この商品について
Conjugate:
unconjugated
Clone:
9H10, monoclonal
Application:
ARR, ICC, IHC, IP, WB
Citations:
19
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
9H10, monoclonal
form
buffered aqueous solution
mol wt
antigen ~34 kDa
species reactivity
human, hamster, monkey, rat, bovine, mouse, canine
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 0.5-1.0 μg/mL using total cell extract of 293T cells
isotype
IgG2b
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HNRNPA1(3178)
mouse ... Hnrnpa1(15382)
rat ... Hnrnpa1(29578)
General description
hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) is a pre-mRNA/mRNA binding protein, that belongs to the hnRNP family. It is located in chromosome 12q13.1. It is located in the nucleoplasm but it travels between the nucleus and the cytoplasm. It has two RNP motif RNA-binding domains (RBDs) at the amino terminus and a glycine-rich domain at the carboxyl terminus.
Immunogen
精製ヒトhnRNP-A1。
Application
Anti-hnRNP-A1 has been used in immunofluorescence, immunohistochemistry and western blotting.
Does not immunoprecipitate the hnRNP complex.
Does not immunoprecipitate the hnRNP complex.
Biochem/physiol Actions
hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) participates in several RNA metabolisms. It also participates in deep vein thrombosis patients with behçet′s disease. hnRNPA1 mutations results in amyotrophic lateral sclerosis and multisystem proteinopathy.
Physical form
0.01M PBS溶液(pH 7.4, 15mMアジ化ナトリウム含有)。
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
R4528-200UL: + R4528-BULK: + R4528-VAR:
jan
関連コンテンツ
HnRNP A1 is Involved in Deep Vein Thrombosis Patients with Behcet's Disease
Chen P, et al.
EBioMedicine, 6, 215-221 (2016)
Carolina Villarroya-Beltri et al.
Nature communications, 4, 2980-2980 (2013-12-21)
Exosomes are released by most cells to the extracellular environment and are involved in cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs (miRNAs) and other non-coding RNAs that can be functionally transferred to recipient cells. However, the mechanisms that
Gabriel S Lopes et al.
Molecular biology reports, 49(6), 4257-4268 (2022-02-23)
We have identified endogenous p65 to be an SDS-stable dimer protein composed of ~ 37 kDa hnRNPA/B-like subunits. We have investigated molecular properties involved in the stability of dimeric form, and their regulation in the transition between monomeric and dimeric forms of hnRNPA/B-like