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Merck

S0327

Scutellarein

≥98% (HPLC)

別名:

4′,5,6,7-Tetrahydroxyflavone, 6-Hydroxyapigenin

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この商品について

実験式(ヒル表記法):
C15H10O6
CAS番号:
分子量:
286.24
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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biological source

Erigeron breviscapus

Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: 1 mg/mL, clear, greenish-yellow

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1)C2=CC(=O)c3c(O)c(O)c(O)cc3O2

InChI

1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H

InChI key

JVXZRQGOGOXCEC-UHFFFAOYSA-N

Biochem/physiol Actions

Flavonoid that is selectively cytotoxic toward cancer cells. Induces mitochondrial ROS, DNA damage, and metabolic suppression, preferentially in tumor cells. Scutellarein has been shown to have better absorption than scutellarin in Caco-2 monolayer cells.


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保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Xiuhua Hao et al.
Journal of pharmaceutical and biomedical analysis, 38(2), 360-363 (2005-06-01)
A validated HPLC method was developed for the quantification of scutellarin in rat plasma using a liquid-liquid extraction and an ultraviolet detection. Chromatographic separation of scutellarin in plasma was performed on a C18 column, with a mobile phase of acetonitrile-water
Anna Berim et al.
Plant physiology, 160(2), 1052-1069 (2012-08-28)
Polymethoxylated flavonoids occur in a number of plant families, including the Lamiaceae. To date, the metabolic pathways giving rise to the diversity of these compounds have not been studied. Analysis of our expressed sequence tag database for four sweet basil
Mi-Sun Yu et al.
Bioorganic & medicinal chemistry letters, 22(12), 4049-4054 (2012-05-15)
Severe acute respiratory syndrome (SARS) is an infectious disease with a strong potential for transmission upon close personal contact and is caused by the SARS-coronavirus (CoV). However, there are no natural or synthetic compounds currently available that can inhibit SARS-CoV.