SAB4200197
モノクロナール抗ペリオスチン マウス宿主抗体
clone 47, purified from hybridoma cell culture
別名:
抗OSF2抗体, 抗PDLPOSTN抗体, 抗POSTN抗体
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この商品について
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
47, monoclonal
Application:
western blot
Species reactivity:
human
Citations:
8
Technique(s):
western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
Uniprot accession no.:
製品名
モノクロナール抗ペリオスチン マウス宿主抗体, clone 47, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
47, monoclonal
form
buffered aqueous solution
mol wt
antigen ~88 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... POSTN(10631)
関連するカテゴリー
General description
Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Application
Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.
Biochem/physiol Actions
Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.
Immunogen
human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
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保管分類
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
SAB4200197-VAR: + SAB4200197-BULK: + SAB4200197-25UL: + SAB4200197-200UL:
jan
Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Makita K, et al.
International Archives of Allergy and Immunology, 175(1-2), 26-35 (2018)
Deepraj Ghosh et al.
Journal of cell science, 133(2) (2020-01-15)
Mesenchymal stem cells (MSCs) are essential for the regenerative process; however, biological aging and environmental stress can induce senescence - an irreversible state of growth arrest - that not only affects the behavior of cells but also disrupts their ability
Bone marrow mesenchymal stem cells promote head and neck cancer progression through Periostin?mediated phosphoinositide 3?kinase/Akt/mammalian target of rapamycin.
Liu C, et al.
Cancer Science, 109(3), 688-698 (2018)
Functional role of periostin in development and wound repair: implications for connective tissue disease.
Hamilton D W.
Journal of Cell Communication and Signaling, 2(1-2), 9-9 (2008)
Epithelial periostin expression is correlated with poor survival in patients with invasive breast carcinoma.
Kim G E, et al.
PLoS ONE, 12(11), e0187635-e0187635 (2017)
関連コンテンツ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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