SAB4502546
Anti-BAX antibody produced in rabbit
affinity isolated antibody
別名:
Apoptosis regulator BAX, BAX, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
14
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 21 kDa
species reactivity
rat, human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BAX(581)
類似した製品をお探しですか？ 訪問 製品比較ガイド
General description
Anti-BAX antibody detects endogenous levels of total BAX protein.
The BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) gene is mapped to human chromosome 19q13.33. It codes for α-helical globular protein. The protein contains eight amphipathic helices around a hydrophobic helix. Bax is known to be mostly localized in the cytoplasm.
Immunogen
The antiserum was produced against synthesized peptide derived from human Bax.
Immunogen Range: 133-182
Immunogen Range: 133-182
Application
Anti-BAX, C-Terminal antibody produced in rabbit has been used in western blotting analysis.
Biochem/physiol Actions
BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) is predominantly associated with cellular homeostasis, cell cycle and pathogenesis of cell death particularly in cancer cells. In response to an apoptotic stimulus, Bax brings about mitochondrial dysfunction and apoptosis. Oligomerization of bax promotes mitochondrial outer membrane permeabilization.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Expression and Prognostic Significance of EP300, TP53 and BAX in Clear Cell Renal Cell Carcinoma.
Godlewski J
Anticancer Research, 37(6), 2927-2937 (2017)
Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
Zhang J
Cell Death & Disease, 7, 1-9 (2016)
Wnt signal transduction pathway and apoptosis: a review.
Pecina-Slaus N
Cancer Cell International, 10:22, 1-5 (2010)
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Garner TP
Molecular Cell, 63(3), 485-497 (2016)
Guo-Liang Zhang et al.
Toxicology and applied pharmacology, 317, 33-40 (2017-01-17)
Zearalenone (ZEA) is an estrogenic mycotoxin mainly produced as a secondary metabolite by numerous species of Fusarium. Previous work showed that ZEA had a negative impact on domestic animals with regard to reproduction. The adverse effects and the mechanisms of
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）