SAB4502960
Anti-TGF β Receptor II antibody produced in rabbit
affinity isolated antibody
別名:
TβR-II, TGF-β receptor type II, TGF-β type II receptor, TGFR-2, Transforming growth factor-β receptor type II
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
7
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 64 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TGFBR2(7048)
General description
Anti-TGF β Receptor II Antibody detects endogenous levels of total TGF β Receptor II protein.
Transforming growth factor β receptor 2 (TGFBR2) is a serine/threonine protein kinase, that belongs to the TGF β receptor subfamily. It is located on human chromosome 3p24.
Transforming growth factor β receptor 2 (TGFBR2) is a serine/threonine protein kinase, that belongs to the TGF β receptor subfamily. It is located on human chromosome 3p24.
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II.
Immunogen Range: 91-140
Immunogen Range: 91-140
Application
Anti-TGF β Receptor II antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Biochem/physiol Actions
Transforming growth factor β receptor 2 (TGFBR2) plays an important role in signal transduction resulting in mitogenic responses. Mutation in TGFBR2 result in Loeys-Dietz syndrome and Marfan syndrome.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
SAB4502960-100UG:
jan
A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix.
Guo Q, et al.
BioMed Research International, 2012, 10-10 (2012)
Arthrogryposis as neonatal presentation of Loeys-Dietz syndrome due to a novel TGFBR2 mutation.
Valenzuela I, et al.
European Journal of Human Genetics, 60(6), 303-307 (2017)
Heterozygous TGFBR2 mutations in Marfan syndrome.
Mizuguchi T, et al.
Nature Genetics, 36(8), 855?860-855?860 (2004)
TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells.
Fricke F, et al.
Cell communication and signaling : CCS, 15(1), 14-14 (2017)
Toshiyuki Ko et al.
Nature communications, 13(1), 3275-3275 (2022-06-08)
Tissue fibrosis and organ dysfunction are hallmarks of age-related diseases including heart failure, but it remains elusive whether there is a common pathway to induce both events. Through single-cell RNA-seq, spatial transcriptomics, and genetic perturbation, we elucidate that high-temperature requirement
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）