T9326
トロンビン ヒト
BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)
別名:
第IIa因子
製品名
トロンビン ヒト, BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)
recombinant
expressed in HEK 293 cells
product line
BioUltra
assay
≥95% (SDS-PAGE)
form
aqueous solution
specific activity
≥2,000 units/mg protein
mol wt
37.4 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
human ... F2(2147)
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Application
トロンビンは、親和性タグを除去するため、アクセス可能なトロンビン認識部位を含むリコンビナント融合タンパク質の部位特異的切断に使用されます。トロンビンは、フランス製の凍結乾燥血漿の止血特性 in vitroで評価するための研究に使用されます。
General description
トロンビンは、止血に関する最終的な凝固プロテアーゼであり、凝固促進作用と抗凝固作用の両方を促進します。
Other Notes
活性は、NIHトロンビン標準物質と直接比較して得られたNIH単位で表されます。
Physical form
20 mM MES、pH 6.0、500 mM塩化コリンの溶液として供給されます。
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Christophe Martinaud et al.
Anesthesiology, 117(2), 339-346 (2012-06-29)
French lyophilized plasma (FLyP) is used routinely by the French Armed Forces in war settings. The authors compared concentrations of coagulation proteins and global in vitro hemostatic properties in FLyP and in the same plasma before lyophilization to assess the
Katerina Zakharova et al.
International journal of molecular sciences, 22(14) (2021-07-25)
Redβ is a 261 amino acid protein from bacteriophage λ that promotes a single-strand annealing (SSA) reaction for repair of double-stranded DNA (dsDNA) breaks. While there is currently no high-resolution structure available for Redβ, models of its DNA binding domain
Ute Metzger et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14309-14314 (2009-08-27)
Ergot alkaloids are toxins and important pharmaceuticals that are produced biotechnologically on an industrial scale. The first committed step of ergot alkaloid biosynthesis is catalyzed by dimethylallyl tryptophan synthase (DMATS; EC 2.5.1.34). Orthologs of DMATS are found in many fungal
Dmitriy Krepkiy et al.
Nature, 462(7272), 473-479 (2009-11-27)
Despite the growing number of atomic-resolution membrane protein structures, direct structural information about proteins in their native membrane environment is scarce. This problem is particularly relevant in the case of the highly charged S1-S4 voltage-sensing domains responsible for nerve impulses
Diane Moujalled et al.
Cell death & disease, 12(1), 133-133 (2021-01-30)
Necroptosis is a pro-inflammatory cell death program executed by the terminal effector, mixed lineage kinase domain-like (MLKL). Previous studies suggested a role for the necroptotic machinery in platelets, where loss of MLKL or its upstream regulator, RIPK3 kinase, impacted thrombosis
資料
Proteases for biotinylated tag removal for protein purification workflows with related reagents and technical resources.
Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.
関連コンテンツ
Instructions
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