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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C21H30O5
CAS 번호:
Molecular Weight:
362.46
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
1354819
MDL number:
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
grade
pharmaceutical primary standard
API family
hydrocortisone
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
mp
211-214 °C (lit.)
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
Gene Information
human ... NR3C1(2908)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Hydrocortisone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Tretinoin, Hydrocortisone and Hydroquinone Cream Miconazole and Hydrocortisone Acetate Cream Hydrocortisone Sodium Succinate Injection Prednisolone Tablets Miconazole and Hydrocortisone Cream Miconazole and Hydrocortisone Ointment Hydrocortisone and Neomycin Cream Hydrocortisone and Clioquinol Ointment Hydrocortisone Sodium Phosphate Oral Solution Prednisolone Gastro-resistant Tablets Hydrocortisone Sodium Phosphate Hydrocortisone Sodium Phosphate Injection Hydrocortisone and Clioquinol Cream Methylprednisolone Tablets Hydrocortisone Acetate Oral Suspension Hydrocortisone Cream Hydrocortisone Oromucosal Tablets
Also used in monographs such as:
Biochem/physiol Actions
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Primary glucocorticoid secreted by the adrenal cortex.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
target_organs
Adrenal gland,Bone marrow
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Psychoneuroendocrinology, 54, 115-123 (2015-02-24)
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Karin E Koopman et al.
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American children consume up to 27% of calories from high-fat and high-sugar snacks. Both sugar and fat consumption have been implicated as a cause of hepatic steatosis and obesity but the effect of meal pattern is largely understudied. We hypothesized
Marianne Oksnes et al.
The Journal of clinical endocrinology and metabolism, 99(5), 1665-1674 (2014-02-13)
Conventional glucocorticoid replacement therapy fails to mimic the physiological cortisol rhythm, which may have implications for morbidity and mortality in patients with Addison's disease. The objective of the study was to compare the effects of continuous sc hydrocortisone infusion (CSHI)
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Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in
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