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Merck

PHR1557

Methylene Chloride

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Dichloromethane, Methylene chloride

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
CH2Cl2
CAS 번호:
Molecular Weight:
84.93
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-838-9
Beilstein/REAXYS Number:
1730800
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1601441

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

1223 °F

expl. lim.

22 %

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Methylene Chloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by gas chromatography (GC) technique.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7796 in the slot below. This is an example certificate only and may not be the lot that you receive.


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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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Methylene Chloride
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 5885-5885 (2018)
Accidental intoxication by dichloromethane at work place: Clinical case and literature review
Pacheco C, et al.
Journal of Acute Medicine, 6(2), 43-45 (2016)
K E Mauck et al.
Integrative and comparative biology, 54(2), 193-209 (2014-04-22)
Recent research suggests that plant viruses, and other pathogens, frequently alter host-plant phenotypes in ways that facilitate transmission by arthropod vectors. However, many viruses infect multiple hosts, raising questions about whether these pathogens are capable of inducing transmission-facilitating phenotypes in